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Monitor Carefully (1)pentobarbital will minimize the level or result of osilodrostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital decreases amounts of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can decrease panobinostat concentrations by ~70% and bring o
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